Hospital-acquired infections resulted in almost 100,000 deaths in 2009 in the US. Hospitals employ re-usable medical instruments in the O/R that are cleaned and sterilized after each surgery. Infections have been tracked to certain instrument types. The FDA now requires all instruments be marked with a UDI (Unique Device Identifier). SignaKey has the only technology capable of marking every instrument. SignaKey marks remain readable through hundreds of sterilization cycles.